| University | City | Type | Level |
| South Dakota State University | Brookings | Public | Four or more years |
| Dakota State University | Madison | Public | Four or more years |
| University of South Dakota | Vermillion | Public | Four or more years |
| Mount Marty College | Yankton | Private not for profit | Four or more years |
| Avera Sacred Heart Hospital | Yankton | Private not for profit | At least 2 but less than 4 years |
| Kilian Community College | Sioux Falls | Private not for profit | At least 2 but less than 4 years |
| Stewart School | Sioux Falls | Private for profit | At least 2 but less than 4 years |
| Sioux Falls Seminary | Sioux Falls | Private not for profit | Four or more years |
| University of Sioux Falls | Sioux Falls | Private not for profit | Four or more years |
| National American University-Sioux Falls | Sioux Falls | Private for profit | Four or more years |
| Southeast Technical Institute | Sioux Falls | Public | At least 2 but less than 4 years |
| Globe University-Sioux Falls | Sioux Falls | Private for profit | Four or more years |
| Colorado Technical University | Sioux Falls | Private for profit | Four or more years |
| Sanford Medical Center | Sioux Falls | Private not for profit | At least 2 but less than 4 years |
| Avera McKennan Hospital School of Radiologic Techn | Sioux Falls | Private not for profit | At least 2 but less than 4 years |
| Augustana College | Sioux Falls | Private not for profit | Four or more years |
| Lake Area Technical Institute | Watertown | Public | At least 2 but less than 4 years |
| Sisseton Wahpeton College | Agency Village | Public | At least 2 but less than 4 years |
| Mitchell Technical Institute | Mitchell | Public | At least 2 but less than 4 years |
| Dakota Wesleyan University | Mitchell | Private not for profit | Four or more years |
| Northern State University | Aberdeen | Public | Four or more years |
| Presentation College | Aberdeen | Private not for profit | Four or more years |
| Sinte Gleska University | Mission | Private not for profit | Four or more years |
| Black Hills Beauty College | Rapid City | Private for profit | At least 2 but less than 4 years |
| Headlines Academy Inc | Rapid City | Private for profit | At least 2 but less than 4 years |
| National American University-Rapid City | Rapid City | Private for profit | Four or more years |
| South Dakota School of Mines and Technology | Rapid City | Public | Four or more years |
| Western Dakota Technical Institute | Rapid City | Public | At least 2 but less than 4 years |
| National American University-Ellsworth AFB Extensi | Ellsworth AFB | Private for profit | Four or more years |
| Oglala Lakota College | Kyle | Public | Four or more years |
| Black Hills State University | Spearfish | Public | Four or more years |
